Anabolic Steroids

Question: In your recent estrogen article, you mentioned Clomid (clomiphene) was safe for long-term use by bodybuilders. But in the World Anabolic Review, the authors say Clomid should be used for no more than 14 days and that it’s a poor estrogen blocker. Also you gave Proviron (mesterolone) a poor mark while the World Anabolic Review claims it’s one of the best estrogen blockers. What’s up? I’m totally confused

Although Colmid isn’t the best of the anti-estrogens, it also has the dual function of mimicking luteinizing hormone, which stimulates gonadal testosterone. So, if you want to lower estrogen and raise testosterone or maintain a natural testosterone level during steroid use, Clomid, if found economically, is an attractive option. I believe the World Anabolic Review writers probably misread the warnings about Clomid and printed the duration of use for women. There are no adverse reactions with long-term use in men that I know of.

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Question: You’re always cutting edge. What’s the next big thing in bodybuilding drugs ? I mean, beyond DNP and insulin, what floats your boat ?

Injectable, once-a-year growth vaccasines-two are being worked on. (more…)

Question: I plan on using insulin, the Humulin R kind, and was wondering if I should take vanadyl and metformin with it ?

Vanadyl and metformin will affect the action of insulin in both good and bad ways. The good thing is less insulin is needed for the small amount of carbohydrates consumed. Increasing the effects of insulin at its lowest possible dosage is the ideal situation. the bad thing is that if you maintain the insulin dosage and food intake levels you had prior to adding vanadyl or metformin, you’d probably get some kind of hypoglycemic reaction, perhaps even go into a coma. The over-the-counter insulin is enticing because it’s cheap and its usefulness is supported by stories from top professional bodybuilders. The underfunded and uninformed recreational bodybuilder, however, may suffer many adverse side effects. Even at moderately low daily dosages of Humulin R, visceral (interorgan) fat will accumulate. At best, this is cosmetically repugnant (men looking pregnant). At worst, visceral fat is associated with heart disease. This fat, at least in male bodybuilders, appears to be the last fat deposit lost when dieting. (more…)

Question: Over the summer, I purchased a few hundred tablets of metformin from a European mail-order company. I started 2,000 mg/ day (one 500-mg tab with meals 4 times a day) and experienced a severe loss of appetite. After ten days, I ceased using the drug because I began to lose weight (muscle) and strength as a result of the lower calorie intake. Do you have any thoughts on this?

I’ve gotten the same reports from other bodybuilders who comment on this loss of appetite. At least you got the dosage right. Most non-diabetics who use Glucophage (the American version of metformin) have been cautious with do sages and haven’t felt any beneficial effects.
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Question: I’m 45 years old, and I’m on testosterone replacement for low natural levels of testosterone–around 300-350 ng/dl. My doctor has prescribed testosterone cypionate (100 mg per week), and this has brought my testosterone level up to around 600 ng/dl. Should I switch over to your recommendation of Deca-Durabolin? Is the use of Deca-Durabolin instead of testosterone for this purpose a documented and accepted practice? One more thing: I’m using 21-gauge needles. Should I try to go to something thinner to minimize scarring?

First off, it’s nice to see you’ve found a liberal doctor. Most M.D.’s won’t consider prescribing testosterone until they see your blood level of testosterone drop below 300 ng/dl. You appear to have an unusual metabolism. Most males of your age would not realize such a high testosterone elevation on only 100 mg a week. Usually a weekly 100-mg injection of testosterone would raise blood levels 100 ng/dl, at the most. What usually happens is that as males age, the ability to convert testosterone to estrogen (with aromatase enzyme) increases. The extra testosterone injected will more readily convert to estrogen and, at the same time, down-regulate the small amount of natural testosterone being produced. I have a strong feeling that your particular metabolism doesn’t manufacture very much aromatase, so the small amount of exogenous testosterone you’re using has better potential, as much of it stays as testosterone and doesn’t down-regulate your own supply. (more…)

Question: Whenever I use clenbuterol, it works great for about two weeks. After that, I can use ten tabs a day and my temperature will hardly rise. What can I do about this?

Clenbuterol is a beta-2 agonist. It attaches to the same receptor as your natural adrenaline and noradrenaline do. It has a very high bonding capacity to the adrenergic receptor. Whenever a drug fits well onto a cell receptor , the receptor becomes resistant to that drug. For example, the thermogenic effect of ephedrine seems to have a longer duration (though it’s not as potent ) for two reasons: 1) ephedrine doesn’t have a high receptor affinity, and 2) ephedrine is not beta-2 specific.

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Question: I was steroid shopping in Tijuana and found some small blue bottles of methandrostenolone made by Ludwig Heun in West Germany (at least, that’s what the bottle said). Is this stuff real?

No. It’s counterfeit. I happen to know the entire history of this counterfeit because I designed the bottle, label, and tablets. (more…)

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