using insulin

Question: I plan on using insulin, the Humulin R kind, and was wondering if I should take vanadyl and metformin with it ?

Vanadyl and metformin will affect the action of insulin in both good and bad ways. The good thing is less insulin is needed for the small amount of carbohydrates consumed. Increasing the effects of insulin at its lowest possible dosage is the ideal situation. the bad thing is that if you maintain the insulin dosage and food intake levels you had prior to adding vanadyl or metformin, you’d probably get some kind of hypoglycemic reaction, perhaps even go into a coma. The over-the-counter insulin is enticing because it’s cheap and its usefulness is supported by stories from top professional bodybuilders. The underfunded and uninformed recreational bodybuilder, however, may suffer many adverse side effects. Even at moderately low daily dosages of Humulin R, visceral (interorgan) fat will accumulate. At best, this is cosmetically repugnant (men looking pregnant). At worst, visceral fat is associated with heart disease. This fat, at least in male bodybuilders, appears to be the last fat deposit lost when dieting.

Metformin was heralded, a few years back, as an “alternative to insulin”, but neither type II diabetics nor bodybuilders have been raving about this drug. What little positive effect metformin has on insulin resistance occurs only at high dosages. We now have hopes for the next generation diabetic drug. Rezulin (troglitazone), recently available here in states. Since Rezulin’s action appears to work on the insulin receptors (increasing their number) and not at the gut level like metformin, it looks like a possible bodybuilding drug. Increasing insulin receptors is a good thing, unless it happens on fat cells, too.

We don’t have a formula for the reduction of insulin when using these insulin synergists. Half the usual dose? Less/more ? From my BODYOPUS experiments. I’ve found a glucometer isn’t accurate blood glucose indicator for readings under 120 dl/ml. I wouldn’t try this stack.

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